{"id":4086,"date":"2021-11-29T10:35:19","date_gmt":"2021-11-29T09:35:19","guid":{"rendered":"https:\/\/itsbrain.mindpulse.net\/?page_id=4086"},"modified":"2022-03-14T12:06:40","modified_gmt":"2022-03-14T11:06:40","slug":"histoire","status":"publish","type":"page","link":"https:\/\/itsbrain.mindpulse.net\/en\/histoire\/","title":{"rendered":"Histoire"},"content":{"rendered":"

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Qui se cache derri\u00e8re MindPulse<\/span>\u00a0?<\/strong><\/h1>\n

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Nous sommes en 1996 et Sandra Suarez entame sa premi\u00e8re th\u00e8se sur le neuro-VIH \u00e0 la Piti\u00e9-Salp\u00eatri\u00e8re. Elle observe que le phe\u0301nome\u0300ne de ralentissement psychomoteur <\/strong>est le meilleur marqueur de l\u2019e\u0301tat neuro-pathologique. Or a\u0300 l\u2019e\u0301poque, elle constate qu\u2019on l\u2019utilise surtout pour identifier des troubles attentionnels sans en comprendre plus explicitement la nature profonde.<\/p>\n

[\/et_pb_text][et_pb_testimonial quote_icon_color=\u00a0\u00bb#151E66″ quote_icon_background_color=\u00a0\u00bb#FFFFFF\u00a0\u00bb _builder_version=\u00a0\u00bb4.14.7″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb border_color_all_portrait=\u00a0\u00bb#151E66″ global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

\u00ab Pendant mes deux post-doc, je vais donc m\u2019int\u00e9resser aux r\u00e9seaux neuronaux et faire de l\u2019imagerie fonctionnelle ce\u0301re\u0301brale, pour essayer de comprendre le lien entre l\u2019attention et la vitesse de transmission nerveuse<\/strong>. J\u2019observe alors que ce qui est fondamentalement en jeu ce sont les grandes boucles sous cortico- frontales \u00bb.<\/span><\/p>\n

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Pendant son second Post-Doc aux c\u00f4tes de Jean-Pierre Changeux a\u0300 l\u2019Institut Pasteur, ce dernier publie un article avec Stanislas Dehaenne, sur un re\u0301seau de neurones mode\u0301lisant l\u2019acce\u0300s a\u0300 la conscience. Sandra comprend que la vitesse de transmission nerveuse<\/strong> est a\u0300 l\u2019origine de la re\u0301ponse et non un e\u0301piphe\u0301nome\u0300ne.<\/p>\n

Anim\u00e9e par l\u2019amour de la recherche, Sandra est soutenue de pr\u00eat par son mari Bertrand Eynard, lui-m\u00eame chercheur en math\u00e9matiques physique<\/strong>. Mais alors qu\u2019elle termine son post-doc, sa carri\u00e8re est boulevers\u00e9e par un cancer tr\u00e8s violent. \u00ab J\u2019ai vraiment ve\u0301cu cette annonce comme un mur contre lequel sont venus se fracasser mes projets, mes espoirs et mes ambitions \u00bb<\/em>.<\/p>\n

Avec pers\u00e9v\u00e9rance et aplomb, Sandra d\u00e9fie les pronostics et vient \u00e0 bout de la maladie. Diminu\u00e9e physiquement, elle fait le choix de ne pas reprendre sa carri\u00e8re de chercheuse de haut niveau et d\u00e9cide d\u2019ouvrir un cabinet de neuropsychologie<\/strong> clinique.<\/p>\n

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\u00ab J\u2019ai e\u0301te\u0301 sid\u00e9r\u00e9e de constater que l\u2019on utilisait encore des tests cre\u0301e\u0301s il y a plus de 70 ans, tous culturellement lie\u0301s, alors que la recherche fondamentale avait fait des progre\u0300s inoui\u0308s dans ce domaine ! Je me suis imme\u0301diatement dit qu\u2019il e\u0301tait urgent de re\u0301inventer<\/strong> la fac\u0327on d\u2019envisager l\u2019e\u0301valuation cognitive<\/strong> pour les fonctions attentionnelles et exe\u0301cutives et d\u2019aller plus loin en essayant de comprendre la part d\u2019interaction avec les e\u0301motions \u00bb<\/span><\/p>\n

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Les origines australiennes du MindPulse<\/span>\u00a0?<\/strong><\/h1>\n

<\/strong><\/h1>\n

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Nous sommes en Australie, Sandra Suarez et sa famille contemplent des crocodiles. Sandra explique a\u0300 ses enfants que si les crocodiles n\u2019agissent pas comme d\u2019habitude et sont ralentis c\u2019est parce qu\u2019il fait froid et que le fonctionnement de<\/span> leur cerveau de\u0301pend de la tempe\u0301rature.<\/p>\n

Une explication qui fait sens pour son mari, Bertrand Eynard, puisque Sandra lui avait expliqu\u00e9\u0301 qu\u2019elle bloquait sur un curseur capable de ralentir ou d\u2019acce\u0301le\u0301rer le cerveau pour avancer sur son id\u00e9e. \u00ab Ce que nous venions pre\u0301cise\u0301ment de comprendre, c\u2019est qu\u2019e\u0302tre lent ne se traduisait pas par le fait de faire la me\u0302me chose plus lentement, mais bien par le fait de faire autre chose, que la vitesse e\u0301tait a\u0300 l\u2019origine du fonctionnement cognitif et non une conse\u0301quence \u00bb, explique Bertrand.<\/p>\n

[\/et_pb_text][et_pb_testimonial quote_icon_color=\u00a0\u00bb#151E66″ quote_icon_background_color=\u00a0\u00bb#FFFFFF\u00a0\u00bb _builder_version=\u00a0\u00bb4.14.7″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb background_color=\u00a0\u00bb#151E66″ border_color_all_portrait=\u00a0\u00bb#151E66″ global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

\u00ab Je me suis alors dit que si nous e\u0301tions capables de mesurer ce ralentissement tre\u0300s pre\u0301cise\u0301ment et de le de\u0301composer en allant observer les diffe\u0301rentiels de vitesse des grandes voies neurologiques, nous pourrions certainement utiliser cette mesure comme un indice du fonctionnement intime des voies neuro-cognitives. Avec Bertrand, nous re\u0301alisons a\u0300 cet instant pre\u0301cis que ce que nous allions devoir mesurer<\/strong>, ce n\u2019e\u0301tait pas le temps, mais la de\u0301ce\u0301le\u0301ration des voies<\/strong> lie\u0301es a\u0300 des ta\u0302ches cognitives particulie\u0300res \u00bb<\/span><\/p>\n

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\u00a0Une intuition qui fait e\u0301cho a\u0300 ses premiers questionnements de recherche,<\/span> mais aussi a\u0300 son constat sans appel du retard des outils d\u2019e\u0301valuation cognitive utilise\u0301s en psychologie clinique.<\/p>\n

Alors que son id\u00e9e suscite imme\u0301diatement l\u2019adhe\u0301sion de ses amis cliniciens, comme le neurologue Jacques Gasnault et de ses anciens colle\u0300gues chercheurs – parmi lesquels Sylvie Granon alors professeure de neurosciences<\/span> a\u0300 l’Institut des neurosciences Paris-Saclay -, Sandra se heurte tre\u0300s vite a\u0300 l\u2019impossibilite\u0301 de financer son projet.<\/p>\n

\u00ab Difficile en effet d\u2019obtenir un financement de recherche quand on entre dans aucune case et un pre\u0302t bancaire quand on a eu un cancer \u00bb, confie-t-elle. Jusqu\u2019au jour ou\u0300 son jeune fils de 8 ans, lui montre le programme informatique qu\u2019il a re\u0301alise\u0301 sur Scratch.<\/p>\n

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\u00ab Je me suis dit que s\u2019il pouvait le faire, je le pouvais aussi. Avec l\u2019aide de Bertrand, je me suis donc lance\u0301e dans la cre\u0301ation d\u2019un pre\u0301-prototype<\/strong> que j\u2019ai pu montrer a\u0300 Sylvie. Il nous a servi de base de travail et, tous les <\/span>trois ensemble, nous l\u2019avons fait e\u0301voluer rapidement. Mais au fur et a\u0300 mesure que nous avancions dans une conception toujours plus complexe, les limites de notre petit logiciel devenaient infranchissables \u00bb.<\/span><\/p>\n

[\/et_pb_testimonial][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00a0\u00bb1″ _builder_version=\u00a0\u00bb4.14.7″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb background_color=\u00a0\u00bb#151E66″ custom_padding=\u00a0\u00bb16px||3px|||\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_row _builder_version=\u00a0\u00bb4.14.1″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb min_height=\u00a0\u00bb90px\u00a0\u00bb custom_padding=\u00a0\u00bb14px|||||\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4″ _builder_version=\u00a0\u00bb4.14.1″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.14.7″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb header_font=\u00a0\u00bb|700|||||||\u00a0\u00bb header_text_align=\u00a0\u00bbcenter\u00a0\u00bb header_text_color=\u00a0\u00bb#151E66″ header_font_size=\u00a0\u00bb41px\u00a0\u00bb custom_margin=\u00a0\u00bb||20px|||\u00a0\u00bb custom_margin_tablet=\u00a0\u00bb||0px|||\u00a0\u00bb custom_margin_phone=\u00a0\u00bb-33px||-29px||false|false\u00a0\u00bb custom_margin_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb header_font_size_tablet=\u00a0\u00bb41px\u00a0\u00bb header_font_size_phone=\u00a0\u00bb34px\u00a0\u00bb header_font_size_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb locked=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

MindPulse<\/span> <\/strong>d\u00e9velopp\u00e9 par IT\u2019S BRAIN<\/span><\/h1>\n

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Sid\u00e9r\u00e9s par les r\u00e9sultats obtenus gr\u00e2ce au MindPulse. Sandra Suarez et Bertrand Eynard sont convaincus qu\u2019il faut d\u00e9velopper une version professionnelle du test.<\/p>\n

Le CNRS identifie alors MindPulse comme une innovation \u00e0 valoriser, ce qui implique la cr\u00e9ation d\u2019une startup comme seul aboutissement. \u00ab Sylvie Granon et Bertrand Eynard e\u0301tant chacun dans un poste de recherche, cela devait reposer sur moi, mais clairement, je n\u2019e\u0301tais pas pre\u0302te ! Apre\u0300s tous les efforts auxquels nous avions consenti, je n\u2019avais aucune envie de me lancer dans la cre\u0301ation d\u2019entreprise. Plus d\u2019une fois, j\u2019ai e\u0301te\u0301 sur le point d\u2019abandonner \u00bb, confie Sandra.<\/p>\n

Avec le soutien de son entourage, Sandra d\u00e9cide de frapper \u00e0 la porte d\u2019IncubAlliance Paris-Saclay pour obtenir des conseils et se former \u00e0 l\u2019entreprenariat. Recherche, clinique et entreprenariat, obtention de la Bourse French Tech, d\u00e9p\u00f4t de brevet conjoint avec le CNRS et l\u2019Universit\u00e9 Paris-Saclay\u2026 <\/span>Sandra est surmen\u00e9e et se met \u00e0 la recherche d\u2019un associ\u00e9. Gr\u00e2ce \u00e0 une amie commune, elle fait la connaissance de Guillaume Simon, polytechnicien et ing\u00e9nieur civil des Mines de Paris. Guillaume est tr\u00e8s rapidement conquis par le projet et d\u00e9cide de s\u2019y impliquer pleinement, <\/span>avec une exp\u00e9rience acquise dans de grandes multinationales <\/span>et en entrepreneuriat<\/span>, pour aider la jeune pousse \u00e0 prendre son envol<\/span>.<\/p>\n

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\u00ab Concre\u0300tement, nous de\u0301cortiquons la vitesse de prise de de\u0301cision<\/strong> sur quatre axes fondamentaux : la vitesse exe\u0301cutive, qui nous parle de l\u2019attention se\u0301lective, la vitesse perceptivo-motrice initiale de chacun e\u0301tant le point de de\u0301part, la pre\u0301cision de la performance et quelque chose en lien avec la mesure de la re\u0301action a\u0300 la difficulte\u0301 de la ta\u0302che \u00bb, explique Bertrand. \u00ab\u00a0On de\u0301taille aussi l\u2019attention et les fonctions exe\u0301cutives<\/strong> dans leurs <\/span>grandes composantes, la se\u0301lectivite\u0301 et l\u2019orientation de l\u2019attention, l\u2019inhibition et la flexibilite\u0301 des fonctions exe\u0301cutives \u00bb, ajoute Sandra.<\/p>\n

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Qui se cache derri\u00e8re MindPulse\u00a0?  Nous sommes en 1996 et Sandra Suarez entame sa premi\u00e8re th\u00e8se sur le neuro-VIH \u00e0 la Piti\u00e9-Salp\u00eatri\u00e8re. Elle observe que le phe\u0301nome\u0300ne de ralentissement psychomoteur est le meilleur marqueur de l\u2019e\u0301tat neuro-pathologique. Or a\u0300 l\u2019e\u0301poque, elle constate qu\u2019on l\u2019utilise surtout pour identifier des troubles attentionnels sans en comprendre plus explicitement […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-4086","page","type-page","status-publish","hentry"],"yoast_head":"\nHistoire - itsbrain<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/itsbrain.mindpulse.net\/en\/histoire\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Histoire - itsbrain\" \/>\n<meta property=\"og:description\" content=\"Qui se cache derri\u00e8re MindPulse\u00a0?  Nous sommes en 1996 et Sandra Suarez entame sa premi\u00e8re th\u00e8se sur le neuro-VIH \u00e0 la Piti\u00e9-Salp\u00eatri\u00e8re. 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